Design, synthesis, and biological evaluation of hydroquinone derivatives as novel inhibitors of the sarco/endoplasmic reticulum calcium ATPase

Stefan PAULA; Josh ABELL; Joel DEYE; Christopher ELAM; Michael LAPE; Justin PURNELL; Robert RATLIFF; Kelly SEBASTIAN; Jodie ZULTOWSKY; Robert J KEMPTON

doi:10.1016/j.bmc.2009.07.075

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Design, synthesis, and biological evaluation of hydroquinone derivatives as novel inhibitors of the sarco/endoplasmic reticulum calcium ATPase

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Design, synthesis, and biological evaluation of hydroquinone derivatives as novel inhibitors of the sarco/endoplasmic reticulum calcium ATPase

Stefan PAULA, Josh ABELL, Joel DEYE, Christopher ELAM, Michael LAPE, Justin PURNELL, Robert RATLIFF, Kelly SEBASTIAN, Jodie ZULTOWSKY and Robert J KEMPTON

Bioorganic & medicinal chemistry, Vol.17(18), pp.6613-6619

2009

DOI: https://doi.org/10.1016/j.bmc.2009.07.075

Handle:

https://hdl.handle.net/20.500.12741/rep:4768

PMCID: PMC2752035

PMID: 19699645

Abstract

Biological and medical sciences

General aspects

Medical sciences

Urinary system

Antineoplastic agents

Pharmacology. Drug treatments

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Title: Design, synthesis, and biological evaluation of hydroquinone derivatives as novel inhibitors of the sarco/endoplasmic reticulum calcium ATPase
Creators: Stefan PAULA - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Josh ABELL - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Joel DEYE - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Christopher ELAM - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Michael LAPE - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Justin PURNELL - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Robert RATLIFF - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Kelly SEBASTIAN - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Jodie ZULTOWSKY - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Robert J KEMPTON - Department of Chemistry, Natural Sciences Center, Northern Kentucky University, Highland Heights, KY 41099-1905, United States
Academic Unit: Chemistry Department
Publisher: Elsevier; Amsterdam
Publication Details: 2009
Identifiers: 99257847452301671; https://hdl.handle.net/20.500.12741/rep:4768; https://doi.org/10.1016/j.bmc.2009.07.075
Language: English