Abstract
Chronic liver disease and liver cirrhosis present major problems for healthcare systems in the United States. Currently, there is no cure for either of these ailments, and both inevitably culminate in liver failure if left untreated. Liver transplantation provides a long-term solution, but the severe shortage of donor organs available to patients results in individuals spending months to years on waiting lists, often resulting in patient deaths prior to the availability of a donor organ. Liver organ bioengineering has been identified as a promising solution to bridge the gap between diagnosis and transplantation.