NF1, NF2, Schwannomatosis, and Dysphagia: A Systematic Review of the Literature Figure 1 Literature Review Flow Identification Screening Included Eligibility

There is a paucity of literature and no established clinical practice for the Ax and Tx of dysphagia in patients with NF1, NF2, or SWN. There is also a lack of information regarding the consequences of dysphagia in patients with NF1, NF2, and SWN. Dysphagia in NF1 and NF2 was frequently identified secondary to the Ax of other health concerns (e.g., tumor progression and/or limb weakness 11,12). Evidence suggests that dysphagia associated with vagal dysfunction due to lower cranial nerve lesions or compression is a risk-factor for aspiration pneumonia and subsequent mortality. Well-designed studies are needed to evaluate the frequency and severity of dysphagia in populations with NF1, NF2, and SWN.